Article
The association of MYO9B gene in Italian patients with inflammatory bowel diseases.
Alimentary pharmacology & therapeutics - 1 Feb 2008
Latiano A, Palmieri O, Valvano M R, D'Incà R, Caprilli R, Cucchiara S, Sturniolo G C, Bossa F, Andriulli A, Annese V
Abstract excerpt
BACKGROUND: Variants of myosin IXB (MYO9B) gene, encoding for a motor protein implicated in epithelial permeability, have been recently associated with inflammatory bowel disease. AIMS: To investigate the contribution of three polymorphisms of MYO9B gene for predisposition to Crohn's disease and ulcerative colitis, their association with clinical phenotypes, particularly intestinal permeability, and possible...
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