Article
EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells.
Oncogene - 9 Apr 2009
Fox B P, Kandpal R P
Abstract excerpt
Breast cancer mortality in women is largely attributed to the metastasis of primary breast tumors. We have analysed the function of EphB6, a kinase-deficient receptor, in the invasive phenotype of breast cancer cell lines. We have demonstrated the loss of EphB6 protein in invasive breast carcinoma cell lines and absence of EphB6 transcript in a metastatic breast tumor specimen. The function of EphB6 in...
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