Article
Transforming Growth Factor-beta Regulation of Ephrin Type-A Receptor 4 Signaling in Breast Cancer Cellular Migration.
Scientific reports - 3 Nov 2017
Hachim Ibrahim Y, Villatoro Manuel, Canaff Lucie, Hachim Mahmood Y, Boudreault Julien, Haiub Halema, Ali Suhad, Lebrun Jean-Jacques
Abstract excerpt
Breast cancer consists of a range of tumor subtypes with different clinical characteristics, disease prognosis, and treatment-response. Luminal breast cancer has the best prognosis while basal-like breast cancer (BLBC) represents the worst subtype. Transforming growth factor-beta (TGFβ) plays a prominent role in stimulating the migration and invasion of malignant breast cancer cells contributing to tumor...
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