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Article

Concomitant PI3K-AKT and p53 alterations in endometrial carcinomas are associated with poor prognosis.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2009

Catasus Lluis, Gallardo Alberto, Cuatrecasas Miriam, Prat Jaime

Abstract excerpt

The status of p53 and the phosphatidylinositol 3-kinase-AKT (PI3K-AKT) signaling pathway was investigated in 132 endometrial carcinomas, including endometrioid endometrial carcinomas, non-endometrioid endometrial carcinomas, and mixed endometrioid adenocarcinomas-non-endometrioid adenocarcinomas. Results were compared with the clinicopathologic parameters associated with prognosis, patients' follow-up, and other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19234438
DOI: 10.1038/modpathol.2009.5

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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