Article
The impact of genomic neighborhood on the evolution of human and chimpanzee transcriptome.
Genome research - 1 May 2009
De Subhajyoti, Teichmann Sarah A, Babu M Madan
Abstract excerpt
Divergence of gene expression can result in phenotypic variation, which contributes to the evolution of new species. Although the influence of trans- and cis-regulatory mutations is well known, the genome-wide impact of changes in genomic neighborhood of genes on expression divergence between species remains largely unexplored. Here, we compare the neighborhood of orthologous genes (within a window of 2 MB) in...
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