Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel polymorphism in CDC6 is associated with the decline in lung function of ex-smokers in COPD.

Biochemical and biophysical research communications - 17 Apr 2009

Takabatake Noriaki, Toriyama Sayumi, Igarashi Akira, Tokairin Yoshikane, Takeishi Yasuchika, Konta Tsuneo, Inoue Sumito, Abe Shuichi, Shibata Yoko, Kubota Isao

Abstract excerpt

The effect of smoking cessation on the rate of decline in lung function in patients with advanced stages of chronic obstructive pulmonary disease (COPD) has not been clarified. Saccharomyces cerevisiae cell division cycle 6 homolog (CDC6) protein possesses the pro-apoptotic properties. We tested our hypothesis that the individual susceptibility to rapid decline in lung function despite smoking cessation in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle Proteins
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Nuclear Proteins

Share to Polymorphism, Single Nucleotide

Share to Pulmonary Disease, Chronic Obstructive

Share to Smoking Cessation

Source

Identifiers

PMID: 19233139
DOI: 10.1016/j.bbrc.2009.02.080

Genes

CDC6
FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel polymorphism in CDC6 is associated with the decline in lung function of ex-smokers in COPD.PMID 19233139Read ↗

Associations of IL6 polymorphisms with lung function decline and COPD.Semantic proximity Read ↗

Genetic variation in PDCD6 and susceptibility to lung cancer.Semantic proximity Read ↗

Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation.Semantic proximity Read ↗

Genome-Wide Association Analysis of Rapid Decline in Lung Function: Analysis From the Korean Genome and Epidemiology Study.Semantic proximity Read ↗

Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease.Semantic proximity Read ↗

Imputation-based association analyses identify new lung cancer susceptibility variants in CDK6 and SH3RF1 and their interactions with smoking in Chinese populations.Semantic proximity Read ↗

Genetic Variants in the Adhesive G Protein-Coupled Receptor ADGRG6 are Associated with Increased Susceptibility to COPD in the Elderly Han Chinese Population of Southern China.Semantic proximity Read ↗

Combined Effects of PVT1 and MiR-146a Single Nucleotide Polymorphism on the Lung Function of Smokers with Chronic Obstructive Pulmonary Disease.Semantic proximity Read ↗

Effect of PRDX6 gene polymorphism on susceptibility to chronic obstructive pulmonary disease in the Chinese Han population.Semantic proximity Read ↗

Genetic variants of pulmonary SP-D predict disease outcome of COPD in a Chinese population.Semantic proximity Read ↗

The programmed cell death 6 interacting protein insertion/deletion polymorphism is associated with non-small cell lung cancer risk in a Chinese Han population.Semantic proximity Read ↗

A novel functional polymorphism in the Cdc6 promoter is associated with the risk for hepatocellular carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.