Article
Activation of sterol regulatory element-binding protein by the caspase Drice in Drosophila larvae.
The Journal of biological chemistry - 10 Apr 2009
Amarneh Bilal, Matthews Krista A, Rawson Robert B
Abstract excerpt
During larval development in Drosophila melanogaster, transcriptional activation of target genes by sterol regulatory element-binding protein (dSREBP) is essential for survival. In all cases studied to date, activation of SREBPs requires sequential proteolysis of the membrane-bound precursor by s...
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