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Article

Discovery of additional members of the tyrosine aminomutase enzyme family and the mutational analysis of CmdF.

Chembiochem : a European journal of chemical biology - 2 Mar 2009

Krug Daniel, Müller Rolf

Abstract excerpt

The tyrosine aminomutase (TAM) CmdF converts L-Tyr preferentially to (R)-beta-Tyr--a biosynthetic building block subsequently incorporated into the highly cytotoxic chondramides by the myxobacterium Chondromyces crocatus. Together with the similar enzymes SgcC4 from Streptomyces globisporus and MdpC4 from Actinomadura madurae, which preferentially produce (S)-beta-Tyr, CmdF belongs to a novel 2,3-aminomutase...

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Source

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PMID: 19222035
DOI: 10.1002/cbic.200800748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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