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Article

Transforming growth factor-{beta}-inducible phosphorylation of Smad3.

The Journal of biological chemistry - 10 Apr 2009

Wang Guannan, Matsuura Isao, He Dongming, Liu Fang

Abstract excerpt

Smad proteins transduce the transforming growth factor-beta (TGF-beta) signal at the cell surface into gene regulation in the nucleus. Upon TGF-beta treatment, the highly homologous Smad2 and Smad3 are phosphorylated by the TGF-beta receptor at the SSXS motif in the C-terminal tail. Here we show...

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Identifiers

PMID: 19218245
DOI: 10.1074/jbc.M809281200
PMCID: PMC2665087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19218245-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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