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Article

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum.

Genome biology - 13 Feb 2009

Dharia Neekesh V, Sidhu Amar Bir Singh, Cassera María Belén, Westenberger Scott J, Bopp Selina Er, Eastman Rich T, Plouffe David, Batalov Serge, Park Daniel J, Volkman Sarah K, Wirth Dyann F, Zhou Yingyao, Fidock David A, Winzeler Elizabeth A

Abstract excerpt

BACKGROUND: The identification of genetic changes that confer drug resistance or other phenotypic changes in pathogens can help optimize treatment strategies, support the development of new therapeutic agents, and provide information about the likely function of genes. Elucidating mechanisms of phenotypic drug resistance can also assist in identifying the mode of action of uncharacterized but potent antimalarial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19216790
DOI: 10.1186/gb-2009-10-2-r21
PMCID: PMC2688282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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