Article
Superoxide dismutases, lung function and bronchial responsiveness in a general population.
The European respiratory journal - 1 May 2009
Siedlinski M, van Diemen C C, Postma D S, Vonk J M, Boezen H M
Abstract excerpt
Oxidative stress is an important causative factor in the onset and progression of smoking-related lung diseases, such as chronic obstructive pulmonary disease (COPD). Superoxide dismutases (SODs) can prevent an increase in oxidative burden. A total of 1,390 subjects from the prospective Vlagtwedde-Vlaardingen cohort were genotyped for two single nucleotide polymorphisms (SNPs) in SOD2 and four SNPs in SOD3, which...
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