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Article

Functional variants of antioxidant genes in smokers with COPD and in those with normal lung function.

Thorax - 1 May 2006

Young R P, Hopkins R, Black P N, Eddy C, Wu L, Gamble G D, Mills G D, Garrett J E, Eaton T E, Rees M I

Abstract excerpt

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is predominantly the consequence of chronic smoking exposure, but its development may be influenced by genetic variants that affect lung remodelling, inflammation, and defence from oxidant stress. A study was undertaken to determine whether genetic variants within genes encoding the antioxidant enzymes superoxide dismutase (SOD) and catalase may be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16467073
DOI: 10.1136/thx.2005.048512
PMCID: PMC2111196

Genes

SOD3
CAT
SOD1
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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