Article
Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine - 15 Apr 2006
Juul Klaus, Tybjaerg-Hansen Anne, Marklund Stefan, Lange Peter, Nordestgaard Børge G
Abstract excerpt
RATIONALE: Increased oxidative stress is involved in chronic obstructive pulmonary disease (COPD); however, plasma and bronchial lining fluid contains the antioxidant extracellular superoxide dismutase. Approximately 2% of white individuals carry the R213G polymorphism in the gene encoding extracellular superoxide dismutase, which increases plasma extracellular superoxide dismutase 10-fold and presumably also...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
