Article
Genetic polymorphisms in antioxidative enzymes are associated to forced expiratory volume in 1 s (FEV1) in smokers independently of asthma.
The clinical respiratory journal - 1 Jan 2012
Malling Tine Halsen, Sigsgaard Torben, Brasch-Andersen Charlotte, Frischknecht Lone, Andersen Helle Raun, Kruse Torben Arvid, Sherson David, Skadhauge Lars Rauff, Thomsen Gert, Baelum Jesper, Omland Øyvind
Abstract excerpt
INTRODUCTION: In this study, we hypothesised that the genotypes coding for low antioxidative enzyme activity are associated with asthma and reduced lung function. METHODS: Using the European Community Respiratory Health Survey protocol, we enlisted 1091 Danish subjects in this cross-sectional study. Asthma phenotypes were defined as asthma symptoms in combination with steroid usage, bronchial hyperresponsiveness...
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