Article
The circadian clock components CRY1 and CRY2 are necessary to sustain sex dimorphism in mouse liver metabolism.
The Journal of biological chemistry - 3 Apr 2009
Bur Isabelle M, Cohen-Solal Anne M, Carmignac Danielle, Abecassis Pierre-Yves, Chauvet Norbert, Martin Agnès O, van der Horst Gijsbertus T J, Robinson Iain C A F, Maurel Patrick, Mollard Patrice, Bonnefont Xavier
Abstract excerpt
In mammals, males and females exhibit anatomical, hormonal, and metabolic differences. A major example of such sex dimorphism in mouse involves hepatic drug metabolism, which is also a noticeable target of circadian timekeeping. However, whether the circadian clock itself contributes to sex-biase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.