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Article

Sex-specific phenotypes of hyperthyroidism and hypothyroidism in mice

23 Aug 2016

Abstract excerpt

BACKGROUND: Thyroid dysfunction is more common in the female population, however, the impact of sex on disease characteristics has rarely been addressed. Using a murine model, we asked whether sex has an influence on phenotypes, thyroid hormone status, and thyroid hormone tissue response in hyper- and hypothyroidism. METHODS: Hypo- and hyperthyroidism were induced in 5-month-old female and male wildtype C57BL/6N...

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PMID: 27559466
DOI: 10.1186/s13293-016-0089-3

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