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CatSper-null mutant spermatozoa are unable to ascend beyond the oviductal reservoir

26 Jan 2009

Abstract excerpt

Sperm hyperactivation is characterised by high-amplitude, asymmetrical flagellar bending and is required to penetrate the oocyte zona pellucida. It was proposed that hyperactivation also enables spermatozoa to reach the oocyte by assisting escape from the oviductal sperm reservoir. To test this hypothesis, the behaviour of CatSper-null mouse spermatozoa in the oviduct was compared with that of spermatozoa from...

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PMID: 19210926
DOI: 10.1071/rd08183

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