Article
Genetic association between interleukin-17 and susceptibility to rheumatoid arthritis.
BMC medical genomics - 6 Nov 2023
Zhao Rong, Zhang Yi-Wen, Yao Jia-Yuan, Qiao Jun, Song Shan, Zhang Sheng-Xiao, Wang Cai-Hong, Li Xiao-Feng
Abstract excerpt
BACKGROUND: The pathogenesis of rheumatoid arthritis (RA) is an immune imbalance, in which various inflammatory immune cells and pro-inflammatory factors are involved. Interleukin-17 (IL-17), a potent pro-inflammatory cytokine, has been found to have increased expression in the joints of patients with RA compared to healthy individuals. However, the causal relationship between the expression level of IL-17 or...
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