Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detecting disease-associated genotype patterns.

BMC bioinformatics - 30 Jan 2009

Long Quan, Zhang Qingrun, Ott Jurg

Abstract excerpt

BACKGROUND: In addition to single-locus (main) effects of disease variants, there is a growing consensus that gene-gene and gene-environment interactions may play important roles in disease etiology. However, for the very large numbers of genetic markers currently in use, it has proven difficult to develop suitable and efficient approaches for detecting effects other than main effects due to single variants....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to Genetic Markers
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 19208180
DOI: 10.1186/1471-2105-10-S1-S75
PMCID: PMC2648768

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detecting disease-associated genotype patterns.PMID 19208180Read ↗

Detecting gene-gene interactions that underlie human diseases.Semantic proximity Read ↗

The role of single nucleotide polymorphisms (SNPs) in understanding complex disorders and pharmacogenomics.Semantic proximity Read ↗

Disease-driven detection of differential inherited SNP modules from SNP network.Semantic proximity Read ↗

Statistical methods in genetics.Semantic proximity Read ↗

A simple and efficient algorithm for genome-wide homozygosity analysis in disease.Semantic proximity Read ↗

MegaSNPHunter: a learning approach to detect disease predisposition SNPs and high level interactions in genome wide association study.Semantic proximity Read ↗

Detecting genetic interactions for quantitative traits with U-statistics.Semantic proximity Read ↗

A method for detecting epistasis in genome-wide studies using case-control multi-locus association analysis.Semantic proximity Read ↗

The usefulness of single nucleotide polymorphisms (SNPs) for genetic epidemiological investigation of complex psychiatric diseases.Semantic proximity Read ↗

Detecting disease comorbidity based on SNP association on PheWAS scale.Semantic proximity Read ↗

The power of independent types of genetic information to detect association in a case-control study design.Semantic proximity Read ↗

SNPxE: SNP-environment interaction pattern identifier.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.