Article
Single Marker Association Analysis for Unrelated Samples.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Zheng Gang, Yuan Ao, Li Qizhai, Gastwirth Joseph L
Abstract excerpt
Methods for single marker association analysis are presented for binary and quantitative traits. For a binary trait, we focus on the analysis of retrospective case-control data using Pearson's chi-squared test, the trend test and a robust test. For a continuous trait, typical methods are based on a linear regression model or the analysis of variance. We illustrate how these tests can be applied using a publicly...
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