Article
CYP4F2 genetic variant (rs2108622) significantly contributes to warfarin dosing variability in the Italian population.
Pharmacogenomics - 1 Feb 2009
Borgiani Paola, Ciccacci Cinzia, Forte Vittorio, Sirianni Elisabetta, Novelli Lucia, Bramanti Placido, Novelli Giuseppe
Abstract excerpt
INTRODUCTION: It is known that warfarin treatment is problematic, due to its narrow therapeutic range and to the great interindividual variability. Numerous papers have shown the important contribution of CYP2C9 and VKORC1 genetic variants to this variability. Recently, a new SNP within the CYP4F...
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