Article
A cooperative interaction between nontranslated RNA sequences and NS5A protein promotes in vivo fitness of a chimeric hepatitis C/GB virus B.
PloS one - 1 Jan 2009
Warter Lucile, Cohen Lisette, Benureau Yann, Chavez Deborah, Yang Yan, Bodola Francis, Lemon Stanley M, Traboni Cinzia, Lanford Robert E, Martin Annette
Abstract excerpt
GB virus B (GBV-B) is closely related to hepatitis C virus (HCV), infects small non-human primates, and is thus a valuable surrogate for studying HCV. Despite significant differences, the 5' nontranslated RNAs (NTRs) of these viruses fold into four similar structured domains (I-IV), with domains...
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