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Article

Genomic determinants of cardiovirulence in coxsackievirus B3 clinical isolates: localization to the 5' nontranslated region.

Journal of virology - 1 May 2000

Dunn J J, Chapman N M, Tracy S, Romero J R

Abstract excerpt

Coxsackievirus B3 (CVB3) infections can cause myocarditis in humans and are implicated in the pathogenesis of dilated cardiomyopathy. The natural genetic determinants of cardiovirulence for CVB3 have not been identified, although using strains engineered in the laboratory, cardiovirulence determinants have been identified in the CVB3 5' nontranslated region (5'NTR) and capsid. The myocarditic phenotypes of two...

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Identifiers

PMID: 10775617
DOI: 10.1128/jvi.74.10.4787-4794.2000
PMCID: PMC112001

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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