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Article

Key Vitamin D Target Genes with Functions in the Immune System

19 Apr 2020

Abstract excerpt

The biologically active form of vitamin D3, 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), modulates innate and adaptive immunity via genes regulated by the transcription factor vitamin D receptor (VDR). In order to identify the key vitamin D target genes involved in these processes, transcriptome-wide datasets were compared, which were obtained from a human monocytic cell line (THP-1) and peripheral blood mononuclear...

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PMID: 32325790
DOI: 10.3390/nu12041140

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