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Article

Clinical implications for statin pleiotropy

7 Nov 2005

Abstract excerpt

PURPOSE OF REVIEW: Atherosclerosis is a multi-factorial condition involving dyslipidemia that can result in cardiovascular disease. Statins are potent inhibitors of cholesterol biosynthesis, and in clinical trials, statins have been shown to be beneficial in the primary and secondary prevention of coronary heart disease. However, the overall benefits observed with statins appear to occur much earlier and to be...

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PMID: 16276239
DOI: 10.1097/01.mol.0000191913.16321.60

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