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Article

Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays.

Nature biotechnology - 1 Apr 2002

Cai Wei-Wen, Mao Jian-Hua, Chow Chi-Wen, Damani Shamsha, Balmain Allan, Bradley Allan

Abstract excerpt

Chromosomal imbalances such as deletions and amplifications are common rearrangements in most tumors. Specific rearrangements are consistently associated with specific tumor types or stages, implicating the role of the genes in a region of chromosomal imbalance in tumor initiation and progression. The development of comparative genomic hybridization (CGH) has obviated the need to obtain metaphase spreads from...

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PMID: 11923847
DOI: 10.1038/nbt0402-393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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