Article
Procarboxypeptidase U (TAFI) contributes to the risk of thrombosis in patients with hereditary thrombophilia.
Thrombosis research - 1 Sept 2009
Heylen Evelien, Miljic Predrag, Willemse Johan, Djordjevic Valentina, Radojkovic Dragica, Colovic Milica, Elezovic Ivo, Hendriks Dirk
Abstract excerpt
INTRODUCTION: It is considered that high plasma levels of procarboxypeptidase U (proCPU or TAFI) can promote the development of thrombosis, but data comparing proCPU levels in thrombophilia carriers and healthy subjects are rather scarce. Moreover, the results of previous studies on the risk of thrombosis related to high proCPU concentration in this population were not consistent. Although the 325 polymorphism of...
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