Article
Routine coagulation tests are not useful as a screening tool for the FII G20210A polymorphism.
Clinical laboratory - 1 Jan 2014
Rolla Roberta, Pergolini Patrizia, Vidali Matteo, Pollarolo Paola, Appiani Alice, Cerutti Chiara, Manzini Matteo, Crisci Alice, Bellomo Giorgio
Abstract excerpt
BACKGROUND: The identification of prothrombin G20210A polymorphism (PT20210) is normally included in the thrombophilia laboratory panel and evaluated by DNA-based molecular analysis. To date, a routine coagulation test that helps to identify PT20210 carriers has not been set, in contrast to the FV Leiden mutation, for which a functional coagulation test, the Activated Protein C Resistance test (APCR), is...
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