Article
Val34Leu polymorphism of plasma factor XIII: biochemistry and epidemiology in familial thrombophilia.
Blood - 1 Oct 2000
Balogh I, Szôke G, Kárpáti L, Wartiovaara U, Katona E, Komáromi I, Haramura G, Pfliegler G, Mikkola H, Muszbek L
Abstract excerpt
Val34Leu polymorphism of the A subunit of coagulation factor XIII (FXIII-A) is located in the activation peptide (AP) just 3 amino acids away from the thrombin cleavage site. This mutation has been associated with a protective effect against occlusive arterial diseases and venous thrombosis; howe...
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