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Article

Relaxation of purifying selection on live attenuated vaccine strains of the family Paramyxoviridae.

Vaccine - 10 Mar 2009

Hughes Austin L

Abstract excerpt

In wild-type sequences of three paramyxoviruses (measles virus, mumps virus, and Newcastle disease virus), nucleotide diversity at both non-coding sites and at nonsynonymous sites in coding regions was significantly reduced in comparison to that at synonymous sites. Likewise, both the mean and variance of gene diversity at nonsynonymous polymorphic sites were reduced in comparison to non-coding and synonymous...

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Identifiers

PMID: 19195493
DOI: 10.1016/j.vaccine.2009.01.036
PMCID: PMC2707849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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