Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Examination of the selective pressures on a live PRRS vaccine virus.

Archives of virology - 1 Jan 1999

Storgaard T, Oleksiewicz M, Bøtner A

Abstract excerpt

We determined the ORF5 and 7 sequences of 20 pathogenic revertants of a live PRRSV vaccine. The sequence analysis confirmed all 20 isolates to be of vaccine origin. Having established that clonal introduction of American (vaccine) PRRS virus had occurred in Denmark, we could perform analysis of the selective pressure this attenuated virus had experienced during reversion. An analysis of nucleotide mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Complementary
Share to Open Reading Frames
Share to Porcine Reproductive and Respiratory Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Porcine respiratory and reproductive syndrome virus

Share to Swine Diseases

Share to Vaccines, Attenuated

Share to Viral Vaccines

Source

Identifiers

PMID: 10664392
DOI: 10.1007/s007050050652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Examination of the selective pressures on a live PRRS vaccine virus.PMID 10664392Read ↗

Reversion of a live porcine reproductive and respiratory syndrome virus vaccine investigated by parallel mutationsSemantic proximity Read ↗

Evolution of Attenuation and Risk of Reversal in Peste des Petits Ruminants Vaccine Strain Nigeria 75/1Semantic proximity Read ↗

A vaccine revertant of highly pathogenic porcine reproductive and respiratory syndrome virus: re-emergence after lurking for 12 yearsSemantic proximity Read ↗

Complete genome comparison of porcine reproductive and respiratory syndrome virus parental and attenuated strains.Semantic proximity Read ↗

Complete genome comparison of porcine reproductive and respiratory syndrome virus parental and attenuated strains.Semantic proximity Read ↗

Mutations of two amino acids in VP5 mediate the attenuation of human rotavirus vaccine: evidence from in vitro and in vivo studies.Semantic proximity Read ↗

Relaxation of purifying selection on the SAD lineage of live attenuated oral vaccines for rabies virus.Semantic proximity Read ↗

Mutation, Selection, and Bottlenecks in Polio Vaccine Reversion.Semantic proximity Read ↗

Circulating type 1 vaccine-derived poliovirus may evolve under the pressure of adenosine deaminases acting on RNA.Semantic proximity Read ↗

Genetic Evolution during the development of an attenuated EIAV vaccine.Semantic proximity Read ↗

Molecular Evolution of Marek's Disease Virus (MDV) Field Strains in a 40-Year Time PeriodSemantic proximity Read ↗

RNA sequence variants in live poliovirus vaccine and their relation to neurovirulence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.