Article
C677T polymorphism of the methylenetetrahydrofolate reductase gene and the risk of ischemic stroke in Polish subjects.
Journal of applied genetics - 1 Jan 2009
Goracy I, Cyryłowski L, Kaczmarczyk M, Fabian A, Koziarska D, Goracy J, Ciechanowicz A
Abstract excerpt
Hyperhomocysteinemia is reported to be an independent risk factor for the development of ischemic stroke. Several studies on genetic variants of methylenetetrahydrofolate reductase (MTHFR, which plays a crucial role in regulation of plasma homocysteine concentration) reported an association betwe...
Topics
- Alleles
- Case-Control Studies
- Female
- Gene Frequency
- Humans
- Ischemia
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Odds Ratio
- Poland
- Polymorphism, Genetic
- Risk
- Risk Factors
- Sex Factors
- Stroke