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Article

Common genetic variants of homocysteine metabolism in ischemic stroke: a case-control study.

European journal of neurology - 1 Aug 2005

Linnebank M, Montenarh M, Kölsch H, Linnebank A, Schnez K, Schweichel D, Pohl C, Urbach H, Heun R, Harbrecht U, Klockgether T, Wüllner U

Abstract excerpt

Hyperhomocysteinemia is a risk factor for ischemic stroke. We investigated five functional polymorphisms involved in homocysteine metabolism in each 159 stroke patients and controls. The folate-sensitive polymorphism methylenetetrahydrofolate reductase (MTHFR) c. 677 C > T (A222V) referred a non-significant risk of ischemic stroke (odds ratio: 1.20) in all patients, and homozygosity for MTHFR c. 677 C > T was...

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Identifiers

PMID: 16053469
DOI: 10.1111/j.1468-1331.2005.01045.x

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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