Article
The T allele of the 677C>T polymorphism of methylenetetrahydrofolate reductase gene is associated with an increased risk of ischemic stroke in Polish children.
Journal of child neurology - 1 Oct 2009
Zak Iwona, Sarecka-Hujar Beata, Kopyta Ilona, Emich-Widera Ewa, Marszal Elzbieta, Wendorff Janusz, Jachowicz-Jeszka Joanna
Abstract excerpt
Ischemic stroke is a very rare and multifactorial disease in children. The aim of the study was to analyze the relationship between the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and stroke in Polish children and to observe whether there is any significant transmission of MTHFR alleles from heterozygous parents to their affected offspring. We analyzed 64 patients with stroke, 122 parents, and...
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