Article

Linked mutations at adjacent nucleotides have shaped human population differentiation and protein evolution

2018-05-23

Abstract excerpt

Despite the fundamental importance of single nucleotide polymorphisms (SNPs) to human evolution there are still large gaps in our understanding of the forces that shape their distribution across the genome. SNPs have been shown to not be distributed evenly, with directly adjacent SNPs found unusually frequently. Why this is the case is unclear. We illustrate how neighbouring SNPs that can’t be explained by a singl...

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Literature Corpus work: ba421833-8930-52ab-8688-ed920ad6c2fe
DOI: 10.1101/329292

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