Article
Molecular mechanism of the interaction between activated factor XIII and its glutamine donor peptide substrate.
Journal of thrombosis and haemostasis : JTH - 1 Apr 2009
Pénzes K, Kövér K E, Fazakas F, Haramura G, Muszbek L
Abstract excerpt
BACKGROUND: Activated factor XIII (FXIII), a dimer of truncated A-subunits (FXIII-A2*), is a transglutaminase that crosslinks primary amines to peptide-bound glutamine residues. Because in the few natural substrates of FXIII-A2* no consensus sequence could be identified around the reactive glutam...
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