Article
Examination of the MSX1 gene in patients with Parkinson's disease.
Acta neurologica Scandinavica - 1 Dec 2009
Deng H, Zhu S H, Le W D, Yang H R, Lv H W, Xu H B, Xie W J, Jankovic J
Abstract excerpt
BACKGROUND: Several genetic variants in transcription factor genes have been reported to be associated with Parkinson's disease (PD). The muscle segment homeobox drosophila homolog of 1 gene (MSX1) is a major upstream regulator of the dopaminergic neuronal subtype specification. AIMS OF THE STUDY: To determine whether genetic variation in the coding region of the MSX1 gene plays a role in the etiology of PD....
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