Article
HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms.
Arthritis and rheumatism - 1 Feb 2009
Lin Y-J, Wan L, Wu J-Y, Sheu J J-C, Lin C-W, Lan Y-C, Lai C-H, Hung C-H, Tsai Y, Tsai C-H, Lin T-H, Lin J-G, Hsueh K-C, Huang Y-M, Chang J-S, Tsai F-J
Abstract excerpt
OBJECTIVE: Kawasaki disease (KD) is a pediatric systemic vasculitis of unknown cause for which a genetic influence is supposed. The purpose of this study was to identify possible genetic variants in the major histocompatibility complex (MHC) region that are associated with KD and the development of coronary artery aneurysms (CAAs) in a Taiwanese population. METHODS: The 168 genetic variants covering the MHC locus...
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