CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children.

doi:10.1038/jhg.2010.154

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Article

CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children.

Journal of human genetics - 1 Feb 2011

Kuo Ho-Chang, Yu Hong-Ren, Juo Suh-Hang Hank, Yang Kuender D, Wang Yu-Shiuan, Liang Chi-Di, Chen Wei-Chiao, Chang Wei-Pin, Huang Chien-Fu, Lee Chiu-Ping, Lin Li-Yan, Liu Yu-Chen, Guo Yuh-Cherng, Chiu Chien-Chih, Chang Wei-Chiao

Abstract excerpt

Kawasaki disease (KD) is characterized by systemic vasculitis of unknown etiology. A study from Japan reported that G to A substitution of a single-nucleotide polymorphism (SNP) located in the 5'-untranslated region of caspase 3 (CASP3) (rs72689236), which was associated with nuclear factor of activated T cell-mediated T-cell activation, is responsible for susceptibility to KD. This study was conducted to...

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PMID: 21160486
DOI: 10.1038/jhg.2010.154

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CASP3

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