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Article

Gene-expression patterns in peripheral blood classify familial breast cancer susceptibility.

BMC medical genomics - 4 Nov 2015

Piccolo Stephen R, Andrulis Irene L, Cohen Adam L, Conner Thomas, Moos Philip J, Spira Avrum E, Buys Saundra S, Johnson W Evan, Bild Andrea H

Abstract excerpt

BACKGROUND: Women with a family history of breast cancer face considerable uncertainty about whether to pursue standard screening, intensive screening, or prophylactic surgery. Accurate and individualized risk-estimation approaches may help these women make more informed decisions. Although highly penetrant genetic variants have been associated with familial breast cancer (FBC) risk, many individuals do not carry...

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Identifiers

PMID: 26538066
DOI: 10.1186/s12920-015-0145-6
PMCID: PMC4634735

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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