Article
Lack of association between beta 2-adrenergic receptor polymorphisms and juvenile idiopathic arthritis.
Scandinavian journal of rheumatology - 1 Jan 2000
Pont-Kingdon G, Bohnsack J, Sumner K, Whiting A, Clifford B, Guthery S S, Jorde L B, Lyon E, Prahalad S
Abstract excerpt
OBJECTIVE: Juvenile idiopathic arthritis (JIA) is a chronic autoimmune arthropathy. Beta 2-adrenergic receptors are a link between the sympathetic nervous system and the immune system. Associations between variants in the gene encoding the beta 2-adrenergic receptor (ADRB2) and autoimmune disorders such as rheumatoid arthritis (RA) have been demonstrated. We aimed to investigate ADRB2 variants for association...
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