Article
Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation.
Genome research - 1 Oct 2003
Lucito Robert, Healy John, Alexander Joan, Reiner Andrew, Esposito Diane, Chi Maoyen, Rodgers Linda, Brady Amy, Sebat Jonathan, Troge Jennifer, West Joseph A, Rostan Seth, Nguyen Ken C Q, Powers Scott, Ye Kenneth Q, Olshen Adam, Venkatraman Ennapadam, Norton Larry, Wigler Michael
Abstract excerpt
We have developed a methodology we call ROMA (representational oligonucleotide microarray analysis), for the detection of the genomic aberrations in cancer and normal humans. By arraying oligonucleotide probes designed from the human genome sequence, and hybridizing with "representations" from ca...
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