Article
Genotypes and in vivo resistance of Plasmodium falciparum isolates in an endemic region of Iran.
Parasitology research - 1 Feb 2007
Heidari Aliehsan, Dittrich Sabine, Jelinek Tomas, Kheirandish Azarmidokht, Banihashemi Kambiz, Keshavarz Hossein
Abstract excerpt
Mutations in the dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) genes of Plasmodium falciparum have been correlated with and used to detect antifolate treatment failure, such as sulfadoxine-pyrimethamine (SP), in regions endemic for malaria. To determine the association betwee...
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