Article
Molecular surveillance of pvdhfr, pvdhps, and pvmdr-1 mutations in Plasmodium vivax isolates from Yunnan and Anhui provinces of China.
Malaria journal - 2 Sept 2014
Huang Bo, Huang Shiguang, Su Xin-zhuan, Tong Xinxin, Yan Junping, Li Hongbin, Lu Fangli
Abstract excerpt
BACKGROUND: Plasmodium vivax is the predominant species of human malaria parasites present in China. Although sulphadoxine-pyrimethamine (SP) and chloroquine (CQ) have been widely used for malaria treatment in China, the resistance profiles of these drugs are not available. Analysis of dihydrofolate reductase (dhfr), dihydropteroate synthase (dhps), and multidrug resistance (mdr-1) gene mutations in P. vivax...
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