Article
Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine.
Malaria journal - 26 Feb 2008
Barnadas Céline, Tichit Magali, Bouchier Christiane, Ratsimbasoa Arsène, Randrianasolo Laurence, Raherinjafy Rogelin, Jahevitra Martial, Picot Stéphane, Ménard Didier
Abstract excerpt
BACKGROUND: Four of five Plasmodium species infecting humans are present in Madagascar. Plasmodium vivax remains the second most prevalent species, but is understudied. No data is available on its susceptibility to sulphadoxine-pyrimethamine, the drug recommended for intermittent preventive treatment during pregnancy. In this study, the prevalence of P. vivax infection and the polymorphisms in the pvdhfr and...
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