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Article

Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation.

Journal of translational medicine - 27 Jan 2009

Veron Philippe, Boutin Sylvie, Martin Samia, Chaperot Laurence, Plumas Joel, Davoust Jean, Masurier Carole

Abstract excerpt

BACKGROUND: Gene modified dendritic cells (DC) are able to modulate DC functions and induce therapeutic immunity or tolerance in an antigen-specific manner. Among the different DC subsets, plasmacytoid DC (pDC) are well known for their ability to recognize and respond to a variety of viruses by secreting high levels of type I interferon. METHODS: We analyzed here, the transduction efficiency of a pDC cell line,...

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Identifiers

PMID: 19173717
DOI: 10.1186/1479-5876-7-10
PMCID: PMC2657113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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