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Article

Consensus siRNA for inhibition of HCV genotype-4 replication.

Virology journal - 27 Jan 2009

Zekri Abdel Rahman N, Bahnassy Abeer A, El-Din Hanaa M Alam, Salama Hosny M

Abstract excerpt

BACKGROUND: HCV is circulating as a heterogeneous group of quasispecies. It has been addressed that siRNA can inhibit HCV replication in-vitro using HCV clone and/or replicon which have only one genotype. The current study was conducted to assess whether siRNA can inhibit different HCV genotypes with many quasispecies and to assess whether consensus siRNA have the same effect as regular siRNA. METHODS: We...

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Share to Cell Line, Tumor
Share to Gene Expression Regulation, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19173711
DOI: 10.1186/1743-422X-6-13
PMCID: PMC2661880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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