Article
Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants.
Blood - 28 May 2009
Opiela Shannon J, Koru-Sengul Tulay, Adkins Becky
Abstract excerpt
In contrast to adults, the murine neonatal CD4+ compartment contains a high frequency of recent thymic emigrants (RTEs). However, the functional capabilities of these cells in neonates are relatively unknown. Moreover, it has not been determined whether RTEs from neonates and adults are comparable. Here we have directly compared neonatal and adult CD4+ RTEs for the first time, using a transgenic mouse strain that...
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