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Article

Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.

Development (Cambridge, England) - 1 Feb 2009

Kawakami Yasuhiko, Uchiyama Yukako, Rodriguez Esteban Concepcion, Inenaga Toshiaki, Koyano-Nakagawa Naoko, Kawakami Hiroko, Marti Merce, Kmita Marie, Monaghan-Nichols Paula, Nishinakamura Ryuichi, Izpisua Belmonte Juan Carlos

Abstract excerpt

The genetic mechanisms that regulate the complex morphogenesis of generating cartilage elements in correct positions with precise shapes during organogenesis, fundamental issues in developmental biology, are still not well understood. By focusing on the developing mouse limb, we confirm the importance of transcription factors encoded by the Sall gene family in proper limb morphogenesis, and further show that they...

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Identifiers

PMID: 19168674
DOI: 10.1242/dev.027748
PMCID: PMC3266482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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