Article
A putative high risk diplotype of the G72 gene is in healthy individuals associated with better performance in working memory functions and altered brain activity in the medial temporal lobe.
NeuroImage - 15 Apr 2009
Jansen Andreas, Krach Sören, Krug Axel, Markov Valentin, Eggermann Thomas, Zerres Klaus, Stöcker Tony, Shah N Jon, Nöthen Markus M, Treutlein Jens, Rietschel Marcella, Kircher Tilo
Abstract excerpt
G72 is a vulnerability gene for schizophrenia and affective psychosis, disorders that are characterized by deficits in working memory. In the present study we investigated whether the G72 genotype influences verbal and spatial working memory functions in healthy individuals. Working memory was assessed at the behavioural level in 423 subjects using the spatial span of the Wechsler Memory Scale (spatial working...
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